Morphology coagulation studies in guinea pigs following injection of vipera russelli venom.

The studies on the morphology of lesions produced and the blood coagulation disturbances after Russell viper envenomation were studied in guinea pigs. The study showed very little morphological changes but the coagulation studies revealed disturbances in coagulation mechanism. The exact pathological process operating in Russell viper emvenomation needs further studies including the histochemical and ultrastructural studies. At present one can only infer that the consumption coagulonathy is the main pathologic change leading to severe bleeding disorders and the death of the animals (JPMA 30:63, 1980).